HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 6-(Bromomethyl)benzo[d]oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 6-Methylbenzoxazole | HCID 2724969 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 6-(Bromomethyl)benzo[d]oxazole | HCID 21985057 | — |
Reaction Steps
6-Methylbenzoxazole was reacted with NBS (1 eq) and catalytic amount of benzoyl peroxide in CCl4 at 90° C. for 12 h to obtain 6-bromomethylbenzoxazole which was purified by flash chromatography (EtOAc:Hexane=1:5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472394B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-b72f49cdb45f447e9eaaeced37fae0f6 |
| Source note | uspto-grants-2002_10 |