Piperazine → HCID 10234179, compound

HRID 993014Notes

Reaction equation

HRID 993014 reaction equation
[CH2:1]([N:8]1[C:12]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[C:16]([O:21][CH3:22])=[C:15]([O:23][CH3:24])[CH:14]=2)=[CH:11][C:10]([CH2:25]Cl)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[CH2:1]([N:8]1[C:12]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[C:16]([O:21][CH3:22])=[C:15]([O:23][CH3:24])[CH:14]=2)=[CH:11][C:10]([CH2:25][N:27]2[CH2:32][CH2:31][N:30]([CH2:25][C:10]3[CH:11]=[C:12]([C:13]4[CH:18]=[C:17]([O:19][CH3:20])[C:16]([O:21][CH3:22])=[C:15]([O:23][CH3:24])[CH:14]=4)[N:8]([CH2:1][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=4)[N:9]=3)[CH2:29][CH2:28]2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 18408498HCID 18408498, compound

Product 1

HCID 10234179HCID 10234179, compound

Procedure

1-Benzyl-3-chloromethyl-5-(3,4,5-trimethoxy-phenyl)pyrazole (559 mg) and piperazine (59 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-a2e01f389a5d4f95a24f4b7ba29bd304
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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