Hydrazine hydrate (1:1) → HCID 178468647, compound

HRID 993016Notes

Reaction equation

HRID 993016 reaction equation
O[C:2]1([O:21][CH3:22])[C:7]([O:8][CH3:9])=[CH:6][CH:5]([CH:10]([CH:16]=[CH2:17])C(OCC)=O)[C:4](=O)[CH:3]1[O:19][CH3:20].[OH2:23].[NH2:24][NH2:25]>>[CH3:9][O:8][C:7]1[CH:6]=[C:5]([C:10]2[NH:25][N:24]=[C:17]([C:9]([O:8][CH2:7][CH3:6])=[O:23])[CH:16]=2)[CH:4]=[C:3]([O:19][CH3:20])[C:2]=1[O:21][CH3:22]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 70152222HCID 70152222, compound

Product 1

HCID 178468647HCID 178468647, compound

Procedure

Ethyl 4-hydroxy-2-oxo-3,4,5-trimethoxyphenyl-3-butenoate (5.0 g) and hydrazine monohydrate (0.8 mL) were treated in the same manner as in Preparation Example 26 to obtain the title compound.

Sources & evidence

ORD record
ord-dcbea1db82f64219a82bfd0577a4bf81
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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