Piperazine → HCID 18408484, compound

HRID 993018Notes

Reaction equation

HRID 993018 reaction equation
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=2)[N:5]([CH2:20][O:21][CH3:22])[N:4]=1.[NH:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[CH3:22][O:21][CH2:20][N:5]1[C:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=2)=[CH:7][C:3]([CH2:2][N:23]2[CH2:28][CH2:27][N:26]([CH2:2][C:3]3[CH:7]=[C:6]([C:8]4[CH:9]=[C:10]([O:18][CH3:19])[C:11]([O:16][CH3:17])=[C:12]([O:14][CH3:15])[CH:13]=4)[N:5]([CH2:20][O:21][CH3:22])[N:4]=3)[CH2:25][CH2:24]2)=[N:4]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 18408536HCID 18408536, compound

Product 1

HCID 18408484HCID 18408484, compound

Procedure

3-Chloromethyl-1-methoxymethyl-5-(3,4,5-trimethoxyphenyl)pyrazole (101 mg) and piperazine (13 mg) were reacted in the same manner in Example 1 to obtain the title compound.

Sources & evidence

ORD record
ord-c52d86cfa3ab405b910066274a47e842
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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