Piperazine → HCID 10210304, compound

HRID 993034Notes

Reaction equation

HRID 993034 reaction equation
Cl[CH2:2][C:3]1[N:4]=[CH:5][N:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=2)[CH:7]=1.[NH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:19][O:18][C:10]1[CH:9]=[C:8]([N:6]2[CH:7]=[C:3]([CH2:2][N:20]3[CH2:25][CH2:24][N:23]([CH2:2][C:3]4[N:4]=[CH:5][N:6]([C:8]5[CH:9]=[C:10]([O:18][CH3:19])[C:11]([O:16][CH3:17])=[C:12]([O:14][CH3:15])[CH:13]=5)[CH:7]=4)[CH2:22][CH2:21]3)[N:4]=[CH:5]2)[CH:13]=[C:12]([O:14][CH3:15])[C:11]=1[O:16][CH3:17]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 18408481HCID 18408481, compound

Product 1

HCID 10210304HCID 10210304, compound

Procedure

4-Chloromethyl-1-(3,4,5-trimethoxyphenyl)imidazole (87 mg) and piperazine (13 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-0ddc4c069afa4af0bed250e3678d5d64
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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