Hydrogen Bromide → HCID 18408835, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 5-(4-Methoxyphenyl)barbituric acid (222 mg) in 3 ml of water, cooled to 0-5° C. with ice bath, are added 136 μl of 48% hydrobromic acid and 56 μl of bromine, dropwise. After 1 hour at a temperature below 10° C., the solid which separated is collected by filtration and washed on the filter with water. The solid is dried for several hours under vacuum at 50° C., to give 283 mg of the product.

Provenance & Evidence