反应详情

温度

65 °C

To a suspension of 3-(4-Methoxyphenyl)propionic acid (10 g) in 150 ml of toluene are added 8 ml of thionyl chloride and the mixture is heated to 65° C. for 4 hours. The solvent is evaporated off under reduced pressure and the residue is redissolved in toluene and concentrated to dryness. Such steo is repeated twice. 11 g of the product are obtained as a yellow oil.

1. customThe solvent is evaporated off under reduced pressure
2. dissolutionthe residue is redissolved in toluene
3. concentrationconcentrated to dryness