HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 5-Bromo-5-(4-methylphenyl)barbituric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 5-(4-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione | HCID 4576911 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Bromo-5-(4-methylphenyl)barbituric acid | HCID 18408658 | — |
Reaction Steps
To a suspension of 5-(4-Methylphenyl)barbituric Acid (218 mg) in 2 ml of water, kept at 10° C. under stirring, 136 μl of 48% hydrobromic acid are added then 56 μl of brominr are dropped and the stirring is continued for 3 hours. The precipitate which formed is recovered by filtration and washed with water, then it is dried under vacuum to give 270 mg of the product, m.p. 210-213° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472396B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-8aed7178812646fea7ef307633128094 |
| Source note | uspto-grants-2002_10 |