Hydrogen Bromide → HCID 54540372, compound

HRID 993075Notes

Reaction equation

HRID 993075 reaction equation
[C:1]1([CH:11]2[C:16](=[O:17])[NH:15][C:14](=[O:18])[NH:13][C:12]2=[O:19])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[BrH:20].BrBr>C(O)C>[Br:20][C:11]1([C:1]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:4]=[CH:3][CH:2]=2)[C:16](=[O:17])[NH:15][C:14](=[O:18])[NH:13][C:12]1=[O:19]

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 69759973HCID 69759973, compound

Product 1

HCID 54540372HCID 54540372, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
0 °C

Procedure

A suspension of 5-naphtylbarbituric Acid (0.2 g) in 1.5 ml of 95% ethanol, cooled at 0° C. and kept under stirring, is added dropwise with 48% hydrobromic acid (0.5 ml) and successively with 4.4 μl of bromine. After 4 hours under stirring at room temperature the solid is filtered and washed with water, then it is dried under vacuum at 40° C. overnight. 0.25 g of the product are obtained.

Workup

  1. stirringAfter 4 hours under stirring at room temperature the solid
  2. filtrationis filtered
  3. washwashed with water
  4. customit is dried under vacuum at 40° C. overnight

Sources & evidence

ORD record
ord-168aac4e77264295b532ec5cb116efcd
Source dataset
uspto-grants-2002_10
Patent number
US06472396B1

Reaction notes

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