反应详情

A mixture of 404.9 mg (1.363 mmol) of compound 18, 239.2 mg (2.156 mmol) of selenium oxide in m-xylene (15 mL) was stirred under refluxed temperature for 21 hours. The reaction mixture was cooled and evaporated. Purification by column chromatography gave 287.0 mg (0.9226 mmol, 67.7% yield) of compound 19.

1. temperatureunder refluxed temperature for 21 hours
2. temperatureThe reaction mixture was cooled
3. customevaporated
4. customPurification by column chromatography