HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxyselenide → 6-Bromo-7-acetoxy-4-formylcoumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxyselenide | HCID 167175 | — |
| Reactant | 6-Bromo-7-acetoxy-4-methylcoumarin | HCID 18410332 | — |
| Solvent | M-Xylene | HCID 7929 | — |
| Product | 6-Bromo-7-acetoxy-4-formylcoumarin | HCID 18410336 | 67.7% |
Reaction Steps
A mixture of 404.9 mg (1.363 mmol) of compound 18, 239.2 mg (2.156 mmol) of selenium oxide in m-xylene (15 mL) was stirred under refluxed temperature for 21 hours. The reaction mixture was cooled and evaporated. Purification by column chromatography gave 287.0 mg (0.9226 mmol, 67.7% yield) of compound 19.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472541B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-79692a787dda457dab549e08bae68c6a |
| Source note | uspto-grants-2002_10 |