HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-[4-(4-Benzylaminosulfonylmethylbenzyl)-phenyl]amino-imidazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-4,5-dihydroimidazole | HCID 236236 | — |
| Reactant | 4-(4-Benzylaminosulfonylmethylbenzyl)-phenylamine | HCID 21876959 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-[4-(4-Benzylaminosulfonylmethylbenzyl)-phenyl]amino-imidazoline | HCID 12094388 | — |
Reaction Steps
A mixture of 4-(4-benzylaminosulfonylmethylbenzyl)-phenylamine (39 mg) and 2-chloro-imidazoline base (1 ea) in 2-propanol was heated under reflux for 16 hours. A dilute solution of potassium carbonate was poured into the mixture and extracted with dichloromethane (4×15 mL). Solvents were evaporated to give 2-[4-(4-benzylaminosulfonylmethylbenzyl)-phenyl]amino-imidazoline as a solid (41.7 mg), m.p. 115-118° C.; Analysis for C24H25ClN4O2S.H2O: Calc.: C, 58.94; H, 5.98; N, 11.46; Found: C, 59.01; H, 5.91; N, 11.30.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472536B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-a4df665ce4334caab781ea256c6d62a9 |
| Source note | uspto-grants-2002_10 |