Trifluoroacetic acid → (1RS,2SR)-2-amino-1-(4-fluorophenyl)-3-[3-(2,2,3,3-tetrafluoropropyl)phenyl]propan-1-ol
Reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([CH2:10][c:11]2[cH:12][c:13]([CH2:17][C:18]([CH:19]([F:20])[F:21])([F:22])[F:23])[cH:14][cH:15][cH:16]2)[NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[OH:32])[cH:6][cH:7]1.[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([CH2:10][c:11]2[cH:12][c:13]([CH2:17][C:18]([CH:19]([F:20])[F:21])([F:22])[F:23])[cH:14][cH:15][cH:16]2)[NH2:24])[OH:32])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-538641f6f71242d9b27c7e4e64e05d90
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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