Methanol → 1-{3-[(4-aminopyrrolo[2,1-f][1,2,4]triazin-5-yl)carbonyl]phenyl}-3-(3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)urea
Reaction equation
[CH3:33][OH:34].[CH3:35][CH2:36][O:37][C:38]([CH3:39])=[O:40].[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8]([C:12](=[O:13])[c:14]1[cH:15][c:16]([NH:20][C:21](=[O:22])[NH:23][c:24]3[cH:25][c:26]([CH:30]4[CH2:31][CH2:32]4)[n:27][n:28]3[CH3:29])[cH:17][cH:18][cH:19]1)[cH:9][c:10]2[Br:11]>>[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8]([C:12](=[O:13])[c:14]1[cH:15][c:16]([NH:20][C:21](=[O:22])[NH:23][c:24]3[cH:25][c:26]([CH:30]4[CH2:31][CH2:32]4)[n:27][n:28]3[CH3:29])[cH:17][cH:18][cH:19]1)[cH:9][cH:10]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2866d2030cd7431799775846b0ca2e85
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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