二氯甲烷 → (+/-)-1-(5-Fluoro-2-hydroxy-phenyl)-1,3-dihydro-isoindole-2-carboxylic acid benzyl ester

反应方程式

[CH:18]([N:19]([CH2:20][CH3:21])[CH:22]([CH3:23])[CH3:24])([CH3:25])[CH3:26].[CH:1]1([c:10]2[c:11]([OH:17])[cH:12][cH:13][c:14]([F:16])[cH:15]2)[NH:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21.[Cl:27][C:28](=[O:29])[O:30][CH2:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[Cl:38][CH2:39][Cl:40]>>[CH:1]1([c:10]2[c:11]([OH:17])[cH:12][cH:13][c:14]([F:16])[cH:15]2)[N:2]([C:28](=[O:29])[O:30][CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21