DL-酒石酸 → HCID 178418492，化合物

HRID 1663

反应方程式

HRID 1663 反应方程式
[C:1]([OH:10])(=[O:9])[CH:2]([CH:4]([C:6]([OH:8])=[O:7])[OH:5])[OH:3].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19]([O:21][C@H:22]2[CH2:27][CH2:26][C@H:25]([C:28]3[CH:33]=[CH:32][C:31]([CH2:34][N:35]([CH3:37])[CH3:36])=[CH:30][CH:29]=3)[CH2:24][CH2:23]2)=[O:20])=[CH:14][CH:13]=1.C(OCC)C>C(O)C>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19]([O:21][C@H:22]2[CH2:23][CH2:24][C@H:25]([C:28]3[CH:29]=[CH:30][C:31]([CH2:34][N:35]([CH3:36])[CH3:37])=[CH:32][CH:33]=3)[CH2:26][CH2:27]2)=[O:20])=[CH:14][CH:13]=1.[C:6]([CH:4]([CH:2]([C:1]([O-:10])=[O:9])[OH:3])[OH:5])([O-:8])=[O:7]

参与物

5

反应物 3

HCID 875DL-酒石酸HCID 3283乙醚HCID 178418347HCID 178418347，化合物

产物 1

HCID 178418492HCID 178418492，化合物

试剂、催化剂与溶剂 1

HCID 702乙醇溶剂

实验过程

First 0.15 g (0.001 mol) of anhydrous tartaric acid and then 0.39 g (0.001 mol) of trans-O-(4-chlorophenylacetyl)-4-(4-dimethylaminomethylphenyl)-cyclohexanol are dissolved in 7 ml of absolute ethanol. Diethyl ether is then added to the clear solution until it becomes slightly cloudy and it is then left to stand for 8 hours at +4° C. The crystalline product precipitated is suction filtered, washed with diethyl ether and dried.

后处理

  1. waitit is then left
  2. customThe crystalline product precipitated
  3. filtrationfiltered
  4. washwashed with diethyl ether
  5. customdried

来源与证据

ORD记录
ord-55aacc7a80b0419cab9d2c65fa6adadb
来源数据集
uspto-grants-1998_03
专利号
US05726205

关联笔记

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