苯甲醛 → Cyclohexyl-(2-phenylimidazo[1,2-a]quinolin-1-yl)-amine

HRID 22801

反应方程式

HRID 22801 反应方程式
[NH2:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[CH:12]1([N+:18]#[C-:19])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[CH:20](=O)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>Cl(O)(=O)(=O)=O>[CH:12]1([NH:18][C:19]2[N:3]3[C:4]4[C:9]([CH:10]=[CH:11][C:2]3=[N:1][C:20]=2[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:8][CH:7]=[CH:6][CH:5]=4)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

参与物

5

反应物 3

HCID 240苯甲醛HCID 113792-氨基喹啉HCID 79129异氰环已烷

产物 1

HCID 17912192Cyclohexyl-(2-phenylimidazo[1,2-a]quinolin-1-yl)-amine

试剂、催化剂与溶剂 1

HCID 24247高氯酸溶剂

实验过程

Compound (15) was prepared according to the general synthesis instructions from 1.0 ml of 2-aminoquinoline solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of benzaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).

来源与证据

ORD记录
ord-5aa9681429dc44d785f771672d9151a9
来源数据集
uspto-grants-2005_02
专利号
US06849642B2

关联笔记

加载中…