四氧化硫 → HCID 21429342，化合物

HRID 437608

反应方程式

HRID 437608 反应方程式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.[OH-].[Na+].[I-].[K+].[I:16]([O-])(=O)=O.[K+].S(=O)(=O)(O)O.S([O-])([O-])=O.[Na+].[Na+]>O.C(O)C>[F:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[C:5]([OH:8])=[C:6]([I:16])[CH:7]=1

参与物

9

反应物 6

HCID 1118四氧化硫HCID 4875碘化钾HCID 14798二甲基对苯二胺二盐酸HCID 24437无水亚硫酸钠HCID 1362362-硝基-4-氟苯酚HCID 23665710Potassium Iodate

产物 1

HCID 21429342HCID 21429342，化合物收率 176.4%

试剂、催化剂与溶剂 2

HCID 702乙醇溶剂HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂2 次

实验过程

A slurry of 4-fluoro-2-nitrophenol (3.3 g), sodium hydroxide (0.83 g), potassium iodide (2.33 g) and potassium iodate (1.5 g) in water (21 ml) was added to a stirred mixture of ethanol (16 ml), water (3.5 ml) and concentrated sulphuric acid (1.7 ml) at 50°. The mixture was heated under reflux for 2 hours and was then allowed to stand at room temperature overnight. A small quantity of sodium sulphite was added to decolourise the product and the yellow solid was filtered and crystallised from aqueous ethanol to give yellow crystalls of 4-fluoro-2-iodo-6-nitrophenol (3.5 g) m.p. 40°.

后处理

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 2 hours
  3. filtrationthe yellow solid was filtered
  4. customcrystallised from aqueous ethanol

来源与证据

ORD记录
ord-e92430831f114d0f9fc0f4e6d18081f9
来源数据集
uspto-grants-1977_06
专利号
US04031249

关联笔记

加载中…