溴代环己烷 → Ethyl 2-[(cyclohexyloxy)imino]-3-oxobutanoate
反应方程式
[OH:1][N:2]=[C:3]([C:9](=[O:11])[CH3:10])[C:4]([O:6][CH2:7][CH3:8])=[O:5].C(=O)([O-])[O-].[K+].[K+].[CH:18]1(Br)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>CN(C)C=O>[CH:18]1([O:1][N:2]=[C:3]([C:9](=[O:11])[CH3:10])[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1参与物
5
实验过程
Ethyl 2-hydroxyimino-3-oxobutyrate (syn isomer, 30 g.), N,N-dimethylformamide (100 ml.), potassium carbonate (39.5 g.) and cyclohexyl bromide (31.1 g.) were treated in a similar manner to that of Example F-(1) to give ethyl 2-cyclohexyloxyimino-3-oxobutyrate (syn isomer, 41.8 g.), oil.
来源与证据
- ORD记录
- ord-d6d540b7eb0a45ebbd68d4755da0bfbb
- 来源数据集
- uspto-grants-1989_04
- 专利号
- US04822888
反应笔记
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