4-Phenylspiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dion

Fluorescamine

HCID 37927CAS 38183-12-9
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
O=C1OC2(OC=C(c3ccccc3)C2=O)c2ccccc21
InChIKey
ZFKJVJIDPQDDFY-UHFFFAOYSA-N
Summenformel
C17H10O4
Durchschnittliche Molmasse
278,26 g/mol
Monoisotopische Masse
278,0579088

Überblick

A nonfluorescent reagent for the detection of primary amines, peptides and proteins. The reaction products are highly fluorescent.

Namen und Bezeichner

Bevorzugter Name
Fluorescamine
IUPAC
4'-phenylspiro[2-benzofuran-3,2'-furan]-1,3'-dione
Lokaler Name
4-Phenylspiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dion
Englischer Name
Fluorescamine
Summenformel
C17H10O4
Molmasse
278.26

Namen und Synonyme

Fluorescamine38183-12-9FluramSpiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione, 4-phenyl-Y6859V58YWDTXSID50872017Spiro(furan-2(3H),1'(3'H)-isobenzofuran)-3,3'-dione, 4-phenyl-RO-20-7234RefChem:388984DTXCID30819622253-814-54'-phenylspiro[2-benzofuran-3,2'-furan]-1,3'-dione
Weitere Namen anzeigen
FluaramFLURAM(R)FluorescaminFluorescamineA.R.Fluorescamine, pureFLURAMANALYTICAL GRADEFluorescamine Labeling
4-Phenylspiro[furan-2(3H),1-phthalan]-3,3'-dioneMFCD00005928EINECS 253-814-5FLUORESCAMINE [MI]4-phenyl-3H,3'H-spiro[furan-2,1'-isobenzofuran]-3,3'-dioneRo 20-7234CS-3522AS-14756

Datenbank-Bezeichner

CAS
38183-12-9
PubChem CID
37927
DTXSID
DTXSID50872017
UNII
Y6859V58YW
EC Number
253-814-5
Nikkaji
J22.287I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
2,9
Polarare Oberfläche (TPSA)
52,6 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
1
Schwere Atome
21

Experimentelle und physikochemische Eigenschaften

Chemical ClassesDyes -> Indicator Dyes
Physical DescriptionOff-white odorless powder; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
153 · 153-157 °C (lit.)
Siedepunkt
381.08 °C · 381.08°C (rough estimate)
Dichte
1.2661 · 1.2661 (rough estimate)
Brechungsindex
1.5447 · 1.5447 (estimate)
Flammpunkt
-17 °C · -17 °C
storage temp.
room temp

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P261, P264+P265, P271, P280, P304+P340, P305+P351+P338, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory InformationSpiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione, 4-phenyl-: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryMay cause irritation; [Alfa Aesar MSDS]

Sicherheitsdaten

F
10-21
wgk
3
ridadr
UN 1090 3/PG 2
hs_code
29322090
risk_code
11-36/38-66-67-36-36/37/38
hazard_code
F,Xi

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 1 Eintrag

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Verwendung und Herstellung

UsesUsed as an analytical reagent; [Merck Index]
Anwendungen · 1 Eintrag

VerwendenFluorescamine is a non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Reaction takes place under mild conditions. Low background due to hydrolysis.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]

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