Sievioside

Stevioside

HCID 442089CAS 57817-89-7
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Grundinformationen

Standard-SMILES
C=C1C[C@@]23CC[C@H]4[C@@](C)(CCC[C@@]4(C)C(=O)O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]2CC[C@]1(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C3
InChIKey
UEDUENGHJMELGK-HYDKPPNVSA-N
Summenformel
C38H60O18
Durchschnittliche Molmasse
804,9 g/mol
Monoisotopische Masse
804,37796506

Namen und Bezeichner

Bevorzugter Name
Stevioside
IUPAC
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
Lokaler Name
Sievioside
Englischer Name
Stevioside
Summenformel
C38H60O18
Molmasse
804.88

Namen und Synonyme

SteviosideSteviosin57817-89-70YON5MXJ9PCHEBI:9271INS NO.960DTXSID7021281FEMA NO. 4763INS-960E-960((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl) (1R,4S,5R,9S,10R,13S)-13-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxan-2-yl)oxy-5,9-dimethyl-14-methylidenetetracyclo(11.2.1.01,10.04,9)hexadecane-5-carboxylate(4bS,8aS)-1-hydroxy-2-isopropyl-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthrene-3,4-dione
Weitere Namen anzeigen
GLUCOSYL STEVIOL GLYCOSIDESSTEVIA LEAF EXTRACTSteviosidesStevia 95% (froM Stevia rebaudiana) anhydrousStevioside (90%)Stevioside powderStevioside - min 80%
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylateRefChem:51134DTXCID301281260-975-5RebaudinDiterpene glycosideSTEVIBIOSIDE.ALPHA.-G-SWEET

Datenbank-Bezeichner

CAS
57817-89-7
PubChem CID
442089
DTXSID
DTXSID7021281
ChEMBL
CHEMBL444122
ChEBI
CHEBI:9271
UNII
0YON5MXJ9P
EC Number
260-975-5
Nikkaji
J27.441K

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,2
Polarare Oberfläche (TPSA)
295 Ų
H-Brücken-Donoren
11
H-Brücken-Akzeptoren
18
Frei drehbare Bindungen
10
Schwere Atome
56

Experimentelle und physikochemische Eigenschaften

Solubility1.25 mg/mL
Melting Point238 - 239 °C
Physical DescriptionSolid
Collision Cross Section269.64 Ų [M+H]+ [CCS Type: TW]

Physikochemische Eigenschaften

Schmelzpunkt
198 °C · 198°C
Siedepunkt
963.3 · 963.3±65.0 °C(Predicted)
Dichte
1.53 · 1.53±0.1 g/cm3(Predicted)
Brechungsindex
-39.3 ° · -39.3 ° (C=6, H2O)
FEMA
4728 · 4728 | GLUCOSYL STEVIOL GLYCOSIDES
storage temp.
2 · Sealed in dry,2-8°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 85.7% (6 of 7) of all reports.

Warning

H315 (14.3%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (14.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (14.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P261, P264, P264+P265, P272, P280, P302+P352, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 6 of 7 reports by companies.；There is 1 notification provided by 1 of 7 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: Kaur-16-en-18-oic acid, 13-[(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy]-, .beta.-D-glucopyranosyl ester, (4.alpha.)-

Kaur-16-en-18-oic acid, 13-(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy-, .beta.-D-glucopyranosyl ester, (4.alpha.)-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (14.3%)；Skin Sens. 1 (14.3%)；Eye Irrit. 2 (14.3%)

Regulatorische Informationen

Regulatory Information · 2 Einträge

Chemical: Kaur-16-en-18-oic acid, 13-[(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy]-, .beta.-D-glucopyranosyl ester, (4.alpha.)-

Kaur-16-en-18-oic acid, 13-(2-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy-, .beta.-D-glucopyranosyl ester, (4.alpha.)-: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
3
hs_code
29389090
RTECS-Nr.
NZ8175000
safety_code
22-24/25
Speicherklasse
11 - Combustible Solids

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationSubstances that sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. (From Random House Unabridged Dictionary, 2d ed)
Cellular LocationsCytoplasm；Extracellular；Membrane

Verwendung und Herstellung

Use Classification · 2 Einträge

Food Additives -> SWEETENER -> JECFA Functional Classes

Cosmetics -> Masking; Oral care

Anwendungen · 2 Einträge

OccurrenceStevioside is a naturally occurring sweetener (～200 times sweeter than sucrose) extracted from a South American plant, Stevia rebaudiana Bertoni. The dried leaves, the water extract of leaves, and the refined chemical ingredients, eg, and Rebaudioside A (～300 times sweeter than sucrose), can all be used as sweetening agents. These are collectively referred to as stevia. Discovered in Paraguay and Brazil, the plant was identified in the early 1970s as a plant of high economical value and transported to Japan for cultivation, where the commercialization of stevia leaves extract as a natural sweetener became a success. Today Stevia plant is cultivated primarily in China.

HistoryBecause no food additive petition has been presented to the FDA, stevioside and related materials cannot be used in the United States as food ingredients. An import alert against stevia was issued by the FDA in 1991. In 1995, however, the FDA revised this import alert to allow the importation and use of stevia as a dietary supplement, but not as a sweetener or an ingredient for foods. In 2004, JECFA (Joint Expert Committee of Food Additives) issued a preliminary ADI (Allowed Daily Intake) of 2-mg/kg body weight (based on steviol) for stevia extract. This action may impact favorably on worldwide regulatory approval. As consumer’s demand on naturally sweetened products increases, interest in Stevia, and naturally occurring potent sweeteners in general, is expected to grow. A comprehensive review of stevia is available [Kinghorn, 2002].

Vor- und nachgelagerte Produkte

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Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

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