1-Cyclopropylpiperazine

HCID 4742004CAS 20327-23-5

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Grundinformationen

Standard-SMILES: C1CN(C2CC2)CCN1
InChIKey: HNZJIWIXRPBFAN-UHFFFAOYSA-N
Summenformel: C7H14N2
Durchschnittliche Molmasse: 126,2 g/mol
Monoisotopische Masse: 126,11569845

Namen und Bezeichner

Bevorzugter Name: 1-Cyclopropylpiperazine
IUPAC: 1-cyclopropylpiperazine
Englischer Name: 1-Cyclopropylpiperazine
Summenformel: C7H14N2
Molmasse: 126.2

Namen und Synonyme

1-Cyclopropylpiperazine20327-23-5DTXSID20406303RefChem:229876DTXCID30357155807-993-7Piperazine, 1-cyclopropyl-MFCD062548051-CYCLOPROPYL-PIPERAZINEcyclopropyl piperazineN-CYCLOPROPYLPIPERAZINE(Piperazin-1-yl)cyclopropane

Weitere Namen anzeigen

1-Cyclopropylpiperazine >(Piperazin-1-yl)cyclopropane1-(Cyclopropyl Phenyl)Piperazine1-Cyclopropylpiperazine - [C14363]1-Cyclopropylpiperazine ISO 9001：2015 REACH

cyclopropylpiperazinecyclopropylpiper-azinen-cyclopropyl-piperazineN-cyclopropyl piperazinePiperazine,1-cyclopropyl-SCHEMBL63548SCHEMBL188355SCHEMBL894571

Datenbank-Bezeichner

CAS: 20327-23-5
PubChem CID: 4742004
DTXSID: DTXSID20406303
EC Number: 807-993-7

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 0,2
Polarare Oberfläche (TPSA): 15,3 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 1
Schwere Atome: 9
Formalladung: 0
Komplexität: 93,1

Physikochemische Eigenschaften

Siedepunkt: 43 °C/7mm · 43°C/7mm
Dichte: 0.94 · 0.94
Brechungsindex: 1.4804 · 1.4804
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Aggregatzustand: clear liquid
pka: 9.23 · 9.23±0.10(Predicted)
Farbe: Colorless to Light yellow
InChI: InChI=1S/C7H14N2/c1-2-7(1)9-5-3-8-4-6-9/h7-8H,1-6H2
InChIKey: HNZJIWIXRPBFAN-UHFFFAOYSA-N
SMILES: N1(C2CC2)CCNCC1

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H302 (60%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Hazard Classes and CategoriesAcute Tox. 4 (60%)

Sicherheitsdaten

ridadr: 3267
hs_code: 2933599590
hazard_code: Xi
hazard_class: 8
packing_group: Ⅲ

Chemie und Industrie

Anwendungen · 1 Eintrag

Verwenden1-cyclopropylpiperazine is a piperazine derivative known in the literature by synonyms such as N-cyclopropylpiperazine and 4-cyclopropylpiperazine. It has been used in the preparation of some tri- and tetrasubstituted ureas with histamine H3 antagonist receptor activity, 3-amido-4- anilinoquinolines series as CSF-1R kinase inhibitors, for the synthesis of cyclopropyl amines as modulators of the histamine H3 receptor, sulfonamide compounds as cysteine protease inhibitors, N-oxides as antibacterial agents and in the treatment of the disease caused by helicobacter infection[1].