Grundinformationen
- Standard-SMILES
CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.Cl- InChIKey
GGWBHVILAJZWKJ-UHFFFAOYSA-N- Summenformel
- C13H23ClN4O3S
- Durchschnittliche Molmasse
- 350,87 g/mol
- Monoisotopische Masse
- 350,11793928
Überblick
See also: Ranitidine Hydrochloride (annotation moved to).
Namen und Bezeichner
- Bevorzugter Name
- Zantac
- IUPAC
- 1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine;hydrochloride
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
66357-59-3、71130-06-8- PubChem CID
- 47909
- DTXSID
DTXSID201015892- UNII
- BK76465IHM
- EC Number
- 275-207-4
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 112 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 9
- Schwere Atome
- 22
- Formalladung
- 0
- Komplexität
- 347
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 54 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
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