Zantac

HCID 47909CAS 66357-59-3

Grundinformationen

Standard-SMILES
CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.Cl
InChIKey
GGWBHVILAJZWKJ-UHFFFAOYSA-N
Summenformel
C13H23ClN4O3S
Durchschnittliche Molmasse
350,87 g/mol
Monoisotopische Masse
350,11793928

Überblick

See also: Ranitidine Hydrochloride (annotation moved to).

Namen und Bezeichner

Bevorzugter Name
Zantac
IUPAC
1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine;hydrochloride

Namen und Synonyme

ZANTACRefChem:934486SantanolTanidinaToriolRadin71130-06-8RaniberlranicDigestosanServiradineAlvidina
Weitere Namen anzeigen
ArtomilAzuranitMideranNoktomeQuadrinRanibertaRanicuxRanidil

Datenbank-Bezeichner

CAS
66357-59-3、71130-06-8
PubChem CID
47909
DTXSID
DTXSID201015892
UNII
BK76465IHM
EC Number
275-207-4

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
112 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
7
Frei drehbare Bindungen
9
Schwere Atome
22

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 54 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.

Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.

Zugehörige Reaktionen

27

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