Natriumcyanat

Large Crystals

Colorless solid; [Merck Index] Beige powder; [Aldrich MSDS]

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P273, P301+P317, P330, and P501 (click each P-code to see the statement)

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P273, P301+P317, P330, and P501 (click each P-code to see the statement)

Chemical: Cyanic acid, sodium salt

Cyanic acid, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Cyanic acid, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-10-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14588

Sodium cyanate: Does not have an individual approval but may be used under an appropriate group standard

Effects on liver (decreased enzyme activity without histopathological changes), blood (increased hematocrit and reticulocytes), male reproductive organs (degeneration of germinal epithelium in the testes), and possible signs of neurotoxicity (reduced activity, impaired coordination, and clonic seizures) observed in 28-day gavage study of rats; Changes in blood interpreted as compensation to increase tissue oxygenation; Following recovery period of six weeks, hematological and neurological effects resolved; High-dose group lowered from 316 to 237 mg/kg/day due to mortality of three animals; [EPA] Causes convulsions in intramuscular LD50 study of rats; Causes degenerative changes to brain and flaccid paralysis without anesthesia in 60-day intramuscular intermittent study of monkeys (2,400 mg/kg); Causes meningeal changes in 60-day subcutaneous intermittent study of monkeys (1,500 mg/kg); Causes flaccid paralysis, somnolence, and other changes to the liver in 3-day oral intermittent study of guinea pigs; (300 mg/kg); Causes abnormal liver function tests in 26-week study of rats at >182 mg/kg; [RTECS] May cause irritation; Harmful by ingestion; [Aldrich MSDS] See Potassium cyanate and Silver cyanate.

Acute Tox. 4 (100%)

Acute toxicity - category 4

Acute toxicity (Oral) - Category 4

Acute Tox. 4 *

Used in experimental treatment of sickle cell anemia; [Merck Index] Used as an intermediate in organic synthesis; [EPA] Used in heat treatment of steel; [Hawley]

Heat Treating [Category: Heat or Machine]

Fabricated Metal Product Manufacturing

Cyanic acid, sodium salt (1:1): ACTIVE