Tetraethylammoniumchlorid
Tetraethylammonium Chloride
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
56-34-8- Standard-SMILES
CC[N+](CC)(CC)CC.[Cl-]- InChIKey
YMBCJWGVCUEGHA-UHFFFAOYSA-M- Summenformel
- C8H20N.Cl
- Durchschnittliche Molmasse
- 165,7 g/mol
- Monoisotopische Masse
- 165,12842732
Überblick
Tetraethylammonium chloride is a quarternary ammonium chloride salt in which the cation has four ethyl substituents around the central nitrogen. It has a role as a potassium channel blocker. It is a quaternary ammonium salt and an organic chloride salt. It contains a tetraethylammonium.
Namen und Bezeichner
- Bevorzugter Name
- Tetraethylammonium Chloride
- IUPAC
- tetraethylazanium chloride
- Lokaler Name
- Tetraethylammoniumchlorid
- Englischer Name
- Tetraethylammonium Chloride
- Summenformel
- C8H20ClN
- Molmasse
- 165.7
Namen und Synonyme
TETRAETHYLAMMONIUM CHLORIDE56-34-8Etamon chlorideTea chlorideTEACN,N,N-Triethylethanaminium chlorideEthanaminium, N,N,N-triethyl-, chloridetetraethylazanium;chlorideDTXSID6041137CHEBI:781618B82Z83XNNDTXCID4021137
Weitere Namen anzeigen
TetraethylammoniumtetraethylazaniuM chlorideSKL1479N2,2,2,2Clammonium chLEthamon chlorideTetraethylammonium choride
RefChem:188563Chloride, Tetraethylammonium200-267-5Tetraethyl ammonium chloridetetraethylammoniumchlorideEt4NClTetraethylammonium (chloride)EINECS 200-267-5
Datenbank-Bezeichner
- CAS
56-34-8- PubChem CID
- 5946
- DTXSID
DTXSID6041137- ChEMBL
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- Polarare Oberfläche (TPSA)
- 0 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 10
- Formalladung
- 0
- Komplexität
- 47,5
Experimentelle und physikochemische Eigenschaften
Chemical ClassesNitrogen Compounds -> Quaternary Amines
Density1.08 @25 °C
Solubility20.3 [ug/mL] (The mean of the results at pH 7.4)
Vapor Pressure0.00000308 [mmHg]
Physical Description
Liquid
Deliquescent solid; [Merck Index] Colorless or light yellow hygroscopic crystals; [Sigma-Aldrich MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 39 °C · 39°C
- Siedepunkt
- 273.32 °C · 273.32°C (rough estimate)
- Dichte
- 1.08 · 1.08
- Brechungsindex
- 1.548 · 1.5480 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- 0.1 g/mL, · methanol: 0.1 g/mL, clear, colorless
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H302 (25.2%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 103 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H320: Causes eye irritation [Warning Serious eye damage/eye irritation]
Gefahrenhinweise
Regulatory Information
Chemical: Ethanaminium, N,N,N-triethyl-, chloride (1:1)
Ethanaminium, N,N,N-triethyl-, chloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, N,N,N-triethyl-, chloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 06-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/20036
Ethanaminium, N,N,N-triethyl-, chloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Tetraethylammonium salts: Human health tier II assessment
Hazards Summary
Causes somnolence, tremor, and muscle weakness in oral, intraperitoneal, and intramuscular lethal-dose studies of mice and rats; Human intravenous injection of 5 mg/kg causes paresthesias, mydriasis, and ptosis; [RTECS] A skin and strong eye irritant; Targets the heart and CNS; [Sigma-Aldrich MSDS] See Tetraethylammonium bromide.
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationA class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
Verwendung und Herstellung
UsesUsed as a catalyst (dehydrogenation and polymerization) and electrolyte (membrane transport studies); [Merck Index]
U.S. Production2023: 1,000,000 - <5,000,000 lb
Industry UsesIntermediate
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
Ethanaminium, N,N,N-triethyl-, chloride (1:1): ACTIVE
Anwendungen
VerwendenTetraethylammonium Chloride can be used as a source of tetraethylammonium ions for various pharmaceutical studies and has the ability to block K+ channels in various tissues. Tetraethylammonium Chloride can also block the transmission of nervous impulses across autonomic ganglions.
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
Zugehörige Reaktionen
185
Notizen zur Verbindung
Wird geladen…