Grundinformationen
- Standard-SMILES
COc1cc(C=CC(=O)O)ccc1O- InChIKey
KSEBMYQBYZTDHS-UHFFFAOYSA-N- Summenformel
- C10H10O4
- Durchschnittliche Molmasse
- 194,18 g/mol
- Monoisotopische Masse
- 194,0579088
Überblick
(E/Z)-ferulic acid has been reported in Camellia reticulata, Angelica gigas, and other organisms with data available.
Namen und Bezeichner
- Bevorzugter Name
- 3-(4-Hydroxy-3-Methoxyphenyl)Prop-2-Enoic Acid
- IUPAC
- 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
- Lokaler Name
- 4-Hydroxy-3-methoxyzimtsure
- Englischer Name
- Ferulic Acid
- Summenformel
- C10H10O4
- Molmasse
- 194.18
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
1135-24-6- PubChem CID
- 709
- DTXSID
DTXSID5040673- ChEMBL
CHEMBL3185646
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 1,5
- Polarare Oberfläche (TPSA)
- 66,8 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 14
- Formalladung
- 0
- Komplexität
- 224
Experimentelle und physikochemische Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 168 · 168-172 °C(lit.)
- Siedepunkt
- 250.62 °C · 250.62°C (rough estimate)
- Dichte
- 1.316 · 1.316(20.0000℃)
- Dampfdruck
- 0 Pa · 0Pa at 25℃
- Brechungsindex
- 1.5168 · 1.5168 (estimate)
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.58 · 4.58±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- slightly yellow
- Wasserlöslichkeit
- soluble
- Kosmetik-Inhaltsstoffe Funktionen
- ANTIOXIDANTANTIMICROBIAL
- InChIKey
- KSEBMYQBYZTDHS-HWKANZROSA-N
- LogP
- 1.51 · 1.51
- CAS Datenbank
- 1135 · 1135-24-6(CAS DataBase Reference)
- NIST chemische Informationen
- 4 · Cinnamic acid, 4-hydroxy-3-methoxy-(1135-24-6)
- EPA chemische Informationen
- Ferulic acid (1135-24-6)
Sicherheit und Regulatorisches
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29162090
- RTECS-Nr.
- UD3365500
- risk_code
- 36/37/38
- Toxizität
- mouse,LD,intraperitoneal,> 350mg/kg (350mg/kg),BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)BEHAVIORAL: ATAXIABEHAVIORAL: REGIDITY,Indian Journal of Pharmaceutical Sciences. Vol. 49, Pg. 77, 1987.
- hazard_code
- Xi
- safety_code
- 26-36-37/39
- hazard_class
- IRRITANT
- Giftige Stoffe Daten
- 1135-24-6(Hazardous Substances Data)
Chemie und Industrie
Anwendungen
BeschreibungFerulic acid is widely found in plants, especially in artichoke, eggplant and corn bran. In addition, it is also present in a variety of Chinese herbal medicines, such as angelica, dome, motherwort, snow ganoderma lucidum and so on.
HistoryFerulic acid was first isolated from the medicinal plants ferulic in 1866. The biologi_x005fcal activity of ferulic acid was not revealed until 1957 when the pioneering study of Preziosi P in Italy showed for the first time the efficacy of ferulic acid in regulating blood lipids and diuretic . In 1979, Lin Mao and others isolated ferulic acid from the Chinese medicine angelica and reported that ferulic acid had the inhibitory effect on platelet aggregation . Since then, more and more medicinal efficacy of ferulic acid has gradually been recognized.
Verwendenferulic acid is a plant-derived anti-oxidant and free-radical scavenger, it protects the skin against uVB-induced redness. When incorporated into formulas with ascorbic acid and tocopherol, ferulic acid can improve their stability and double the photoprotection capacities offered by the formulation. In clinical studies, ferulic acid exhibits good permeation capacities through the stratum corneum, which can be attributed to its lipophilic properties.
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Ergänzende Hinweise
DefinitionA plant growth inhibitor.
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