4-Hydroxy-3-methoxyzimtsure

3-(4-Hydroxy-3-Methoxyphenyl)Prop-2-Enoic Acid

HCID 709CAS 1135-24-6

Grundinformationen

Standard-SMILES
COc1cc(C=CC(=O)O)ccc1O
InChIKey
KSEBMYQBYZTDHS-UHFFFAOYSA-N
Summenformel
C10H10O4
Durchschnittliche Molmasse
194,18 g/mol
Monoisotopische Masse
194,0579088

Überblick

(E/Z)-ferulic acid has been reported in Camellia reticulata, Angelica gigas, and other organisms with data available.

Namen und Bezeichner

Bevorzugter Name
3-(4-Hydroxy-3-Methoxyphenyl)Prop-2-Enoic Acid
IUPAC
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Lokaler Name
4-Hydroxy-3-methoxyzimtsure
Englischer Name
Ferulic Acid
Summenformel
C10H10O4
Molmasse
194.18

Namen und Synonyme

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acidRefChem:1066861(E/Z)-ferulic acid(2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylic acidTrans-3-(4-hydroxy-3-methoxyphenyl)acrylic acid3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acidferulic acid (trans-4-hydroxy-3-methoxycinnamic acid)EINECS 214-490-0CIS-FERULICACIDbmse000587DTXSID70892035ferulasaur
Weitere Namen anzeigen
Ferulate4-HYDROXY-3-METHOXYCINNAMIC ACIDFerulic3-METHOXY-4-HYDROXYCINNAMIC ACIDFERULLIC ACIDferulaic aciderulic AcidForulic acidFERULIC ACID pureTIMTEC-BB SBB000326
4-Hydroxy-3-methoxy cinnamic acidBBL010345AC-7965Ferulic acid CRStrans-Ferulic Acid (purified by sublimation)Spectrum_001256SpecPlus_000547Spectrum2_001394

Datenbank-Bezeichner

CAS
1135-24-6
PubChem CID
709
DTXSID
DTXSID5040673
ChEMBL
CHEMBL3185646

Eigenschaften

Berechnete Struktureigenschaften

XLogP
1,5
Polarare Oberfläche (TPSA)
66,8 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
3
Schwere Atome
14

Experimentelle und physikochemische Eigenschaften

LogP1.87

Physikochemische Eigenschaften

Schmelzpunkt
168 · 168-172 °C(lit.)
Siedepunkt
250.62 °C · 250.62°C (rough estimate)
Dichte
1.316 · 1.316(20.0000℃)
Dampfdruck
0 Pa · 0Pa at 25℃
Brechungsindex
1.5168 · 1.5168 (estimate)
storage temp.
2 · 2-8°C

Sicherheit und Regulatorisches

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
29162090
RTECS-Nr.
UD3365500
risk_code
36/37/38
Toxizität
mouse,LD,intraperitoneal,> 350mg/kg (350mg/kg),BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)BEHAVIORAL: ATAXIABEHAVIORAL: REGIDITY,Indian Journal of Pharmaceutical Sciences. Vol. 49, Pg. 77, 1987.

Chemie und Industrie

Anwendungen · 3 Einträge

BeschreibungFerulic acid is widely found in plants, especially in artichoke, eggplant and corn bran. In addition, it is also present in a variety of Chinese herbal medicines, such as angelica, dome, motherwort, snow ganoderma lucidum and so on.

HistoryFerulic acid was first isolated from the medicinal plants ferulic in 1866. The biologi_x005fcal activity of ferulic acid was not revealed until 1957 when the pioneering study of Preziosi P in Italy showed for the first time the efficacy of ferulic acid in regulating blood lipids and diuretic . In 1979, Lin Mao and others isolated ferulic acid from the Chinese medicine angelica and reported that ferulic acid had the inhibitory effect on platelet aggregation . Since then, more and more medicinal efficacy of ferulic acid has gradually been recognized.

Verwendenferulic acid is a plant-derived anti-oxidant and free-radical scavenger, it protects the skin against uVB-induced redness. When incorporated into formulas with ascorbic acid and tocopherol, ferulic acid can improve their stability and double the photoprotection capacities offered by the formulation. In clinical studies, ferulic acid exhibits good permeation capacities through the stratum corneum, which can be attributed to its lipophilic properties.

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国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
西安天朗源生物科技有限公司17749038280 17749038280 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

Ergänzende Hinweise

DefinitionA plant growth inhibitor.

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