2-(2-Aminoethyl)pyridin
2-Pyridineethanamine
Grundinformationen
- CAS
2706-56-1- Standard-SMILES
NCCc1ccccn1- InChIKey
XPQIPUZPSLAZDV-UHFFFAOYSA-N- Summenformel
- C7H10N2
- Durchschnittliche Molmasse
- 122,17 g/mol
- Monoisotopische Masse
- 122,08439833
Überblick
2-pyridylethylamine is an aminoalkylpyridine that is pyridine substituted by a ethanamino group at position 2. It has a role as a metabolite and a histamine agonist. It is a primary amine and an aminoalkylpyridine. It is functionally related to a pyridine.
Namen und Bezeichner
- Bevorzugter Name
- 2-Pyridineethanamine
- IUPAC
- 2-pyridin-2-ylethanamine
- Lokaler Name
- 2-(2-Aminoethyl)pyridin
- Englischer Name
- 2-Pyridylethylamine
- Summenformel
- C7H10N2
- Molmasse
- 122.17
Namen und Synonyme
2-(2-Aminoethyl)pyridine2706-56-12-Pyridylethylamine2-(2-Pyridyl)ethylamine2-Pyridineethanamine2-pyridin-2-ylethanamineDemethylbetahistinealpha-PyridylethylaminePyridine, 2-(2-aminoethyl)-ATW1AH7OJ5NSC-71989DTXSID5022196
Weitere Namen anzeigen
lilly04432RARECHEM AL BW 02582-aminoethylpyridine2-pyridineethylamine
CHEBI:74024RefChem:453308Lilly-044322-(beta-Aminoethyl)pyridineDTXCID502196LY 04432220-295-12-(pyridin-2-yl)ethanamine
Datenbank-Bezeichner
- CAS
2706-56-1- PubChem CID
- 75919
- DTXSID
DTXSID5022196- ChEMBL
CHEMBL32813- ChEBI
CHEBI:74024- UNII
- ATW1AH7OJ5
- EC Number
- 220-295-1
- Nikkaji
- J150.806G
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,1
- Polarare Oberfläche (TPSA)
- 38,9 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 9
- Formalladung
- 0
- Komplexität
- 73,3
Experimentelle und physikochemische Eigenschaften
LogP0.08
Physikochemische Eigenschaften
- Schmelzpunkt
- 198 · 198-200 °C(Solv: ethanol (64-17-5))
- Siedepunkt
- 93 °C; · 93 °C; 199 °F; 366 K at 1.6 kPa
- Dichte
- 1.021 g · 1.021 g cm−3
- Brechungsindex
- 1.536 · 1.536
- Flammpunkt
- 100 °C · 100 °C (212 °F; 373 K)
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 1 · pK1: 4.24(+2);pK2: 9.78(+1) (25°C,μ=0.05)
- Aggregatzustand
- clear liquid
- Farbe
- Colorless to Light orange to Yellow
- Wichte
- 1.021 · 1.021
- Wasserlöslichkeit
- Soluble in water (partly), and most common polar solvent. Insoluble in non-polar solvents, and oils.
- BRN
- 111208 · 111208
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H314 (14.9%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 47 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Corr. 1B (14.9%)
Sicherheitsdaten
- F
- 10-34
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- 2735
- hs_code
- 2933399090
- risk_code
- 36/37/38-34
- hazard_code
- Xi
- safety_code
- 26-36-45-36/37/39
- hazard_class
- 8
- packing_group
- III
- Speicherklasse
- 10 - Combustible liquids
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationDrugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically.
Verwendung und Herstellung
General Manufacturing Information2-Pyridineethanamine: ACTIVE
Anwendungen
Verwenden2-(2-Aminoethyl)pyridine is used as active pharmaceutical ingredients.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
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