(+-)-Methionine

HCID 876CAS 26062-47-5

Grundinformationen

Standard-SMILES
CSCCC(N)C(=O)O
InChIKey
FFEARJCKVFRZRR-UHFFFAOYSA-N
Summenformel
C5H11NO2S
Durchschnittliche Molmasse
149,21 g/mol
Monoisotopische Masse
149,05104977

Namen und Bezeichner

Bevorzugter Name
(+-)-Methionine
IUPAC
2-amino-4-methylsulfanylbutanoic acid
Englischer Name
POLY-L-METHIONINE
Summenformel
C5H11NO2S
Molmasse
149.21

Namen und Synonyme

DL-METHIONINE59-51-8RacemethionineAcimetionLobamineUrimeth(+-)-MethionineDL-MethioninumMethionine, DL-2-amino-4-methylsulfanylbutanoic acid2-amino-4-(methylsulfanyl)butanoic acidFEMA No. 3301
Weitere Namen anzeigen
Nsc118113Poly(Met)polymethioninePOLY-L-METHIONINEPOLY-L-METHIONINE USP/EP/BP2-amino-4-methylsulfanylbutanoicaci
Methionine, amorphousMethionine DL-DL-2-Amino-4-(methylthio)-butyric acidDTXSID9020821NSC-924173JWT2K6T3DTXCID50821CHEBI:16811

Datenbank-Bezeichner

CAS
26062-47-5、33807-07-7、348-67-4、59-51-8、63-68-3
PubChem CID
876
DTXSID
DTXSID9020821
ChEMBL
CHEMBL274119
ChEBI
CHEBI:16811
UNII
73JWT2K6T3
EC Number
200-432-1
Nikkaji
J1.286F

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,9
Polarare Oberfläche (TPSA)
88,6 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
4
Schwere Atome
9

Experimentelle und physikochemische Eigenschaften

DensityRelative density (water = 1): 1.3
Solubility · 4 Einträge

32.7 mg/mL at 25 °C

Solubility in water, g/100ml at 20 °C: 4.8

Soluble in water; Insoluble in ether

Soluble (in ethanol)

Boiling Point300.00 to 301.00 °C. @ 760.00 mm Hg
Decomposition281 °C
Melting Point281 °C
Physical Description · 4 Einträge

Solid; [Merck Index] Colorless or white solid; [ICSC] White powder; [Sigma-Aldrich MSDS]

Solid

COLOURLESS CRYSTALS OR WHITE POWDER.

White crystalline platelets or powder; Characteristic aroma

Physikochemische Eigenschaften

storage temp.
-20 °C · -20°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 99% (197 of 199) of all reports.

Not Classified;Reported as not meeting GHS hazard criteria by 197 of 199 companies (only 1% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 199 reports by companies from 4 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 197 of 199 reports by companies.;There are 2 notifications provided by 2 of 199 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: DL-Methionine

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Methionine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methionine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Methionine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - DL-Methionine: Human health tier I assessment;IMAP assessments - DL-Methionine: Environment tier I assessment
Fire HazardsGives off irritating or toxic fumes (or gases) in a fire.
Hazards Summary · 1 Eintrag

Causes pigmented or nucleated red blood cells, changes in leukocyte counts, and changes in liver, bladder, and spleen weights in repeated-dose oral studies of rats; [RTECS] No listed effects of short-term or long-term exposure; [ICSC] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; [Sigma-Aldrich MSDS]

EPA Safer ChemicalChemical: DL-Methionine; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Chemical DangersDecomposes on heating. This produces toxic fumes of sulfur oxides and nitrous oxides.

Sicherheit und Schutzausrüstung

Fire FightingUse water spray, powder, foam, carbon dioxide.
First Aid Measures · 4 Einträge

Fresh air, rest.

Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

Safe StorageSeparated from strong oxidants. Well closed.
Spillage DisposalSweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Eye PreventionWear safety spectacles.
Ingestion PreventionDo not eat, drink, or smoke during work.

Toxikologische Informationen

Exposure RoutesThe substance can be absorbed into the body by ingestion.

Regulatorische Informationen

Regulatory Information · 4 Einträge

Chemical: DL-Methionine

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Methionine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methionine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Methionine: Does not have an individual approval but may be used under an appropriate group standard

Chemie und Industrie

Pharmakologische Informationen

Cellular LocationsCytoplasm;Extracellular

Verwendung und Herstellung

UsesAn essential amino acid; Used therapeutically as an antidote for acetaminophen poisoning and a urinary acidifier; [Merck Index] Used as a flavoring agent and nutritional supplement; [FDA]
U.S. Production2021: 246,400 lb
Industry UsesNot Known or Reasonably Ascertainable
Use Classification · 5 Einträge

EPA Safer Chemical Functional Use Classes -> Enzymes and Enzyme Stabilizers

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Cosmetics -> Antistatic; Hair conditioning; Skin conditioning

General Manufacturing Information · 2 Einträge

Not Known or Reasonably Ascertainable

Methionine: ACTIVE

Anbieter6 Anbieter

上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
宝鸡缔都医药化工有限公司029-81145305 17791533577 · [email protected]
石家庄瑞田生化有限公司15831127780 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
DONBOO AMINO ACID COMPANY13063595538 · [email protected]

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