Guaiacol → ((o-Methoxyphenoxy)methyl)oxirane

HRID 1017247Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1017247
[C:1]1([O:8][CH3:9])[C:2](=[CH:4][CH:5]=[CH:6][CH:7]=1)[OH:3].CC(C)([O-])C.[K+].[CH2:16]([CH:18]1[O:20][CH2:19]1)Cl.C1OCCOCCOCCOCCOCCOC1>C(O)(C)(C)C.O>[O:20]1[CH2:19][CH:18]1[CH2:16][O:3][C:2]1[CH:4]=[CH:5][CH:6]=[CH:7][C:1]=1[O:8][CH3:9]

Komponenten

7

Edukt 4

HCID 460GuaiacolHCID 7835EpichlorohydrinHCID 2855718-Crown-6HCID 23665647Potassium tert-butoxide

Produkt 1

HCID 98357((o-Methoxyphenoxy)methyl)oxirane

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 6386tert-ButanolLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

Guaiacol (8.6 g, 69 mmol), potassium t-butoxide (7.8 g, 69 mmol), epichlorohydrin (19.3 g, 209 mmol), and 18-crown-6 (0.8 g) were mixed in t-butanol (100 ml) and heated to 50° C. for 2 h. Water was added and the product was extracted with two portions of dichlorometane. Washing with water, twice, was followed by drying and evaporation. Quantitative yield.

Aufarbeitung

  1. extractionthe product was extracted with two portions of dichlorometane
  2. washWashing with water
  3. customby drying
  4. customevaporation

Quellen und Nachweise

ORD-Eintrag
ord-7f06efcd61404ef7987c209d8f77713a
Quelldatensatz
uspto-grants-2002_11
Patentnummer
US06479491B1

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