Triethylamine → 1-Fluoro-2-[(trifluoromethyl)sulfanyl]benzene

HRID 1045159Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1045159
[F:1][C:2](I)([F:4])[F:3].[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[SH:13].C(N(CC)CC)C>CN(C)C=O.O>[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13][C:2]([F:4])([F:3])[F:1]

Komponenten

6

Edukt 3

HCID 8471TriethylamineHCID 16843TrifluoroiodomethaneHCID 5202162-Fluorothiophenol

Produkt 1

HCID 470028801-Fluoro-2-[(trifluoromethyl)sulfanyl]benzene

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

Methyl viologen hydrochloride (1.17 g) in N,N-dimethylformamide (80 mL) at 25° C. was saturated with trifluoromethyl iodide, treated with 2-fluorobenzenethiol (9.7 mL) and triethylamine (20 mL), stirred for 24 hours, diluted with water (240 mL) and extracted with diethyl ether. The extract was washed with 1M NaOH, saturated ammonium chloride and brine and concentrated.

Aufarbeitung

  1. customat 25° C.
  2. extractionextracted with diethyl ether
  3. washThe extract was washed with 1M NaOH, saturated ammonium chloride and brine
  4. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-e5991bfa76b94b27be2b99a7db65ab37
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08563735B2

Notizen zur Reaktion

Wird geladen…