Hydrochloric Acid → 1-{5-[3-(Aminosulfonyl)phenyl]-6-(4-fluorophenyl)-2-(trifluoro methyl)pyrimidin-4-yl}piperidine-4-carboxylic acid
Reaktionsgleichung
[ClH:42].[Li+:41].[NH2:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7](-[c:11]2[c:12]([N:28]3[CH2:29][CH2:30][CH:31]([C:34](=[O:35])[O:36][CH2:37][CH3:38])[CH2:32][CH2:33]3)[n:13][c:14]([C:24]([F:25])([F:26])[F:27])[n:15][c:16]2-[c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)[cH:8][cH:9][cH:10]1.[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[OH-:40].[OH2:39].[OH2:48]>>[NH2:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7](-[c:11]2[c:12]([N:28]3[CH2:29][CH2:30][CH:31]([C:34](=[O:35])[OH:36])[CH2:32][CH2:33]3)[n:13][c:14]([C:24]([F:25])([F:26])[F:27])[n:15][c:16]2-[c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)[cH:8][cH:9][cH:10]1
