Oxalyl chloride → HCID 23445624, Verbindung

HRID 1067361Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1067361
[CH2:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([CH2:14][CH3:15])[C:11]=1[O:12][CH3:13])[C:6]([OH:8])=O)[CH3:2].C(Cl)(=O)C(Cl)=O.[Sn].[CH2:23]([C:30]1[O:31][C:32]([CH3:36])=[C:33]([CH3:35])[CH:34]=1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([C:30]1[O:31][C:32]([CH3:36])=[C:33]([CH3:35])[C:34]=1[C:6]([C:5]1[CH:9]=[C:10]([CH2:14][CH3:15])[C:11]([O:12][CH3:13])=[C:3]([CH2:1][CH3:2])[CH:4]=1)=[O:8])[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Komponenten

5

Edukt 4

HCID 65578Oxalyl chlorideHCID 5352426Tin atomHCID 15895031HCID 15895031, VerbindungHCID 234456633.5-Diethyl-4-methoxybenzoic acid

Produkt 1

HCID 23445624HCID 23445624, Verbindung

Versuchsvorschrift

The title compound was prepared according to the procedure in Example 5, step 2, using 3,5-diethyl-4-methoxybenzoic acid (10.66 g, 51.3 mmol), oxalyl chloride (4.90 mL, 56.3 mmol), N,N-DMF (2 drops), tin IV chloride (6.60 mL, 56.3 mmol) and 2-benzyl-4,5-dimethylfuran (11.4 g, 61.3 mmol) to give 22.0 g, of the title compound. 1H NMR δ1.13 (t, 6H), 1.83 (s, 3H), 2.19 (s, 3H), 2.61 (q, 4H), 3.74 (s, 3H), 3.82 (s, 2H), 7.05 (d, 2H), 7.23-7.27 (m, 3H), 7.42 (s, 2H). mass spectrum (EI), m/z 376 (M+).

Aufarbeitung

  1. customThe title compound was prepared
  2. customto give 22.0 g

Quellen und Nachweise

ORD-Eintrag
ord-c3d08b1ee743495d8db61d4fa1939c14
Quelldatensatz
uspto-grants-2001_06
Patentnummer
US06248764B1

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