Water → N-methyl-2H-3-isoquinolone

HRID 1075819

Reaktionsgleichung

Reaktionsgleichung von HRID 1075819
S(O)(O)(=O)=O.[CH3:6][N:7]1[C:16](=[O:17])[CH:15]=[C:14]2[C:9]([CH:10]=[CH:11][CH:12]=[CH:13]2)=[CH:8]1.O.C(=O)(O)[O-].[Na+]>C(Cl)(Cl)Cl>[CH3:6][N:7]1[C:16](=[O:17])[CH:15]=[C:14]2[C:9]([CH:10]=[CH:11][CH:12]=[CH:13]2)=[CH:8]1

Komponenten

5

Edukt 3

HCID 962WaterHCID 516892Sodium BicarbonateHCID 21541268N-methyl-2H-3-isoquinolone sulfate

Produkt 1

HCID 12435498N-methyl-2H-3-isoquinolone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel2×

Versuchsvorschrift

70 g. N-methyl-2H-3-isoquinolone sulfate are dissolved, under an atmosphere of nitrogen, in 900 ml. water. 75 g. sodium bicarbonate are added and the mixture is stirred with 500 ml. chloroform. By decantation, there is obtained a chloroform solution of N-methyl-2H-3-isoquinolone, which can be dried over anhydrous sodium sulfate and employed as such or concentrated for a further reaction.

Quellen und Nachweise

ORD-Eintrag
ord-c078a18486cf4a12876c27b719da7b99
Quelldatensatz
uspto-grants-1976_05
Patentnummer
US03954771

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