Bromine → 2-Bromo-7-nitro-3,4-dihydronaphthalen-1(2H)-one

HRID 1086847Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1086847
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][C:11]2=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:15]Br>CCOCC>[Br:15][CH:10]1[CH2:9][CH2:8][C:7]2[C:12](=[CH:13][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[C:11]1=[O:14]

Komponenten

4

Edukt 2

HCID 24408BromineHCID 384457-Nitro-1-tetralone

Produkt 1

HCID 131941302-Bromo-7-nitro-3,4-dihydronaphthalen-1(2H)-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To a suspension of 9.56 g (0.05 mol) of 7-nitro-1-tetralone in 250 mL of ether was added bromine dropwise. The progress of the reaction was followed by thin layer chromatography (fl. silica gel/CH2Cl2). When all of the starting material had been consumed, the mixture was concentrated and cyclohexane was added. The white solid was removed by filtration to afford 2.25 g of 2-bromo-7-nitrotetralone, mp 94°-96° C.

Aufarbeitung

  1. customWhen all of the starting material had been consumed
  2. concentrationthe mixture was concentrated
  3. additioncyclohexane was added
  4. customThe white solid was removed by filtration

Quellen und Nachweise

ORD-Eintrag
ord-d3ed7897c4024e418d5b32db5db3219e
Quelldatensatz
uspto-grants-1991_07
Patentnummer
US05032598

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