Water → 4-Morpholino-2-nitrobenzonitrile

HRID 1091531

Reaktionsgleichung

Reaktionsgleichung von HRID 1091531
[N+:1]([C:4]1[CH:11]=[C:10]([N+:12]([O-])=O)[CH:9]=[CH:8][C:5]=1[C:6]#[N:7])([O-:3])=[O:2].N1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1.O>CN(C)C=O>[N:12]1([C:10]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([N+:1]([O-:3])=[O:2])[CH:11]=2)[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

Komponenten

5

Edukt 3

HCID 962WaterHCID 8083MorpholineHCID 5540822,4-Dinitrobenzonitrile

Produkt 1

HCID 134992654-Morpholino-2-nitrobenzonitrileAusbeute 82,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

A mixture of 2,4-dinitrobenzonitrile 4.20 g (21.75 mmol) and morpholine 5.7 mL (66.0 mmol) in N,N-dimethylformamide 20 mL was stirred at room temperature for 20 hours. The reaction mixture was poured into water. The precipitate was collected and washed with water to give the title compound 4.20 g as orange solid. Yield 74.5%.

Aufarbeitung

  1. customThe precipitate was collected
  2. washwashed with water

Quellen und Nachweise

ORD-Eintrag
ord-02cebe0ec2ed4d2abe6ec47f4a5a4591
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08129386B2

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