4-Nitroisophthalic acid → 4-Aminobenzene-1,3-dioic acid

HRID 1094730

Reaktionsgleichung

Reaktionsgleichung von HRID 1094730
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=1[C:13]([OH:15])=[O:14])([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=1[C:13]([OH:15])=[O:14]

Komponenten

4

Edukt 1

HCID 30624384-Nitroisophthalic acid

Produkt 1

HCID 113558524-Aminobenzene-1,3-dioic acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 4-nitro isophthalic acid (4 g, 18.95 mmol) in MeOH (200 mL) was added Pd/C (20%) and the mixture was hydrogenated at RT over night. The reaction mixture was filtered through Celite and filtrate concentrated under vacuum to give 4-amino isophthalic acid in 60% as a solid.

Aufarbeitung

  1. waitthe mixture was hydrogenated at RT over night
  2. filtrationThe reaction mixture was filtered through Celite and filtrate
  3. concentrationconcentrated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-a70aad4b64f84b4ba0494f54b48628cb
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08133998B2

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