Dimethylformamide → HCID 57930995, Verbindung

HRID 1096984Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1096984
[CH2:1](I)[CH3:2].CN(C=O)C.[Br:9][C:10]1[C:19]([O:20][CH3:21])=[CH:18][C:13]([C:14]([O:16][CH3:17])=[O:15])=[CH:12][C:11]=1[OH:22].C(=O)([O-])[O-].[K+].[K+]>O>[Br:9][C:10]1[C:19]([O:20][CH3:21])=[CH:18][C:13]([C:14]([O:16][CH3:17])=[O:15])=[CH:12][C:11]=1[O:22][CH2:1][CH3:2]

Komponenten

6

Edukt 4

HCID 6228DimethylformamideHCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 57930973HCID 57930973, Verbindung

Produkt 1

HCID 57930995HCID 57930995, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

In a 1.0-liter egg plant-type flaks, ethyl iodide (6.91 mL, 86 mmol) was added to a DMF (150 mL) solution of the previously-obtained methyl 4-bromo-3-hydroxy-5-methoxybenzoate and potassium carbonate (11.9 g, 86 mmol), and stirred overnight at room temperature. Water was added to the reaction solution, the formed precipitate was taken out through filtration and dried under reduced pressure to obtain the title compound as a colorless solid.

Aufarbeitung

  1. filtrationthe formed precipitate was taken out through filtration
  2. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-764ac02837e64c8ab08283cb874b6954
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08138197B2

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