Sodium Cyanide → Fenvalerate

HRID 1112605

Reaktionsgleichung

Reaktionsgleichung von HRID 1112605
[O:1]([C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH:11]=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([CH:23]([CH:27]([CH3:29])[CH3:28])[C:24](Cl)=[O:25])=[CH:19][CH:18]=1.[C-:30]#[N:31].[Na+]>O.CCCCCCC>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([CH:23]([CH:27]([CH3:29])[CH3:28])[C:24]([O:12][CH:11]([C:30]#[N:31])[C:10]2[CH:13]=[CH:14][CH:15]=[C:8]([O:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH:9]=2)=[O:25])=[CH:19][CH:18]=1

Komponenten

6

Edukt 3

HCID 8929Sodium Cyanide3×HCID 382843-PhenoxybenzaldehydeHCID 41780012-(4-Chlorophenyl)-3-methylbutanoyl chloride

Produkt 1

HCID 3347Fenvalerate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittel2×HCID 8900HeptaneLösungsmittel

Versuchsvorschrift

A 500 ml round-bottomed flask equipped with a paddle stirrer was charged with 100 mmol of 3-phenoxybenzaldehyde, 100 mmol of 2-(4-chlorophenyl)-3-methylbutanoyl chloride, 120 mmol of sodium cyanide, 10 ml of water, and 200 ml of n-heptane. The molar ratio of water to sodium cyanide was 4.64, all NaCN being dissolved. The mixture thus formed was stirred and analysed. Table VI presents the yields and purities of the desired ester after the reaction time indicated.

Aufarbeitung

  1. customA 500 ml round-bottomed flask equipped with a paddle stirrer
  2. customThe mixture thus formed
  3. customyields

Quellen und Nachweise

ORD-Eintrag
ord-dced4548778d4b5fbc68b4a165a71eaa
Quelldatensatz
uspto-grants-1978_10
Patentnummer
US04123451

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