Pyridine, 2-(4-methoxyphenoxy)-5-(trifluoromethyl)- → 4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

HRID 1155474

Reaktionsgleichung

Reaktionsgleichung von HRID 1155474
C[O:2][C:3]1[CH:19]=[CH:18][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][N:9]=2)=[CH:5][CH:4]=1.Cl.N1C=CC=CC=1>O.Cl>[OH:2][C:3]1[CH:19]=[CH:18][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:15])[F:16])=[CH:10][N:9]=2)=[CH:5][CH:4]=1

Komponenten

5

Edukt 2

HCID 155242Pyridine, 2-(4-methoxyphenoxy)-5-(trifluoromethyl)-HCID 10176127Pyridinium chloride

Produkt 1

HCID 1552414-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 313Hydrochloric AcidLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

The product from (c) (1.7 g) and excess of pyridine hydrochloride were heated together for 8 hours at 180° C. The mixture was cooled, diluted with water and 2-molar hydrochloric acid, and extracted with ether. The extracts were dried and evaporated to yield an oil identified as the required hydroxy compound.

Aufarbeitung

  1. temperatureThe mixture was cooled
  2. extractionextracted with ether
  3. customThe extracts were dried
  4. customevaporated
  5. customto yield an oil

Quellen und Nachweise

ORD-Eintrag
ord-b2b93f581afd4ba08de951bf7d3c848f
Quelldatensatz
uspto-grants-1981_11
Patentnummer
US04302242

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