2-[2-Methoxy-3-(3-chlorophenoxy)phenyl]acetic acid → 2-[2-Hydroxy-3-(3-chlorophenoxy)phenyl]acetic acid
Reaktionsgleichung
C[O:2][C:3]1[C:8]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:17][C:18]([OH:20])=[O:19]>C(OC(=O)C)(=O)C.I>[OH:2][C:3]1[C:8]([O:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:17][C:18]([OH:20])=[O:19]Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A solution of 2-[2-methoxy-3-(3-chlorophenoxy)phenyl]acetic acid (10 g) in acetic anhydride (30 ml) and 48% hydriodic acid (60 ml) were treated in a similar manner to that of Example 6-(6) to give 2-[2-hydroxy-3-(3-chlorophenoxy)phenyl]acetic acid (4.6 g). mp 99°-102° C.