Nitric Acid → 1-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane

HRID 1166996Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1166996
[C:1]([O:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]2[O:13][CH2:14][O:15][C:9]=2[CH:8]=1)(=[O:3])[CH3:2].[N+:16]([O-])([OH:18])=[O:17].O>C(O)(=O)C>[C:1]([O:4][CH2:5][CH2:6][C:7]1[C:12]([N+:16]([O-:18])=[O:17])=[CH:11][C:10]2[O:13][CH2:14][O:15][C:9]=2[CH:8]=1)(=[O:3])[CH3:2]

Komponenten

5

Edukt 3

HCID 944Nitric AcidHCID 962WaterHCID 3030742-(1,3-Benzodioxol-5-yl)ethyl acetate

Produkt 1

HCID 234454281-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethaneAusbeute 88 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

To a stirred solution of 1-acetoxy-2-[(3,4-methylenedioxy)phenyl]ethane (1.7 g, 8.09 mmol) in acetic acid (10 ml) was added, dropwise, concentrated HNO3 (4.5 ml). This was stirred at room temperature for 30 min. The reaction mixture was poured into water (100 ml). The precipitated solid was filtered, washed with water and dried under high vacuum to get 1-acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane (1.8 g, 88% yield).

Aufarbeitung

  1. filtrationThe precipitated solid was filtered
  2. washwashed with water
  3. customdried under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-f477f4337a3947cebc8aec7eb6b4af03
Quelldatensatz
uspto-grants-2003_09
Patentnummer
US06613804B2

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