Pivalaldehyde → 2,2-Dimethyl-5-hexen-3-ol

HRID 1174314Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1174314
[CH3:1][C:2]([CH3:6])([CH3:5])[CH:3]=[O:4].[CH2:7]([Mg]Br)[CH:8]=[CH2:9]>C(OCC)C>[CH3:1][C:2]([CH3:6])([CH:3]([OH:4])[CH2:9][CH:8]=[CH2:7])[CH3:5]

Komponenten

4

Edukt 2

HCID 12417PivalaldehydeHCID 178455850HCID 178455850, Verbindung

Produkt 1

HCID 1405562,2-Dimethyl-5-hexen-3-ol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

A solution of trimethylacetaldehyde (10.2 mL, 90.9 mmol) in diethyl ether (200 mL) at 0° C. was treated with allylmagnesium bromide (100 mL, 1 M in ether), stirred at 0° C. for 1 hour, quenched with saturated ammonium chloride and extracted with diethyl ether. The organic phase was washed with brine and dried over Na2SO4, filtered and concentrated to give the title compound (11.6 g).

Aufarbeitung

  1. customquenched with saturated ammonium chloride
  2. extractionextracted with diethyl ether
  3. washThe organic phase was washed with brine
  4. dry with materialdried over Na2SO4
  5. filtrationfiltered
  6. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-b43ebccd1ac24905b74a717053e46356
Quelldatensatz
uspto-grants-2010_11
Patentnummer
US07834043B2

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