Sodium Iodide → Silane, (5-iodo-1-pentynyl)trimethyl-

HRID 1197372

Reaktionsgleichung

Reaktionsgleichung von HRID 1197372
Cl[CH2:2][CH2:3][CH2:4][C:5]#[C:6][Si:7]([CH3:10])([CH3:9])[CH3:8].[I-:11].[Na+]>CC(=O)CC>[I:11][CH2:2][CH2:3][CH2:4][C:5]#[C:6][Si:7]([CH3:10])([CH3:9])[CH3:8]

Komponenten

4

Edukt 2

HCID 5238Sodium IodideHCID 27579421-Chloro-5-(trimethylsilyl)-4-pentyne

Produkt 1

HCID 11140046Silane, (5-iodo-1-pentynyl)trimethyl-Ausbeute 93,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6569Methyl Ethyl KetoneLösungsmittel

Versuchsvorschrift

A mixture of 5-chloro-1-trimethylsilylpent-1-yne (13.5 g) and sodium iodide (29 g) in butanone (100 ml) was heated at reflux for 10 hours. After this time the solvent was removed in vacuo and the residue partitioned between diethyl ether and water. The organic phase was separated, washed with water and brine before drying over anhydrous magnesium sulphate. The solvent was removed under reduced pressure to leave 5-iodo-1-trimethylsilylpent-1-yne as a colourless oil (19.3 g).

Aufarbeitung

  1. temperaturewas heated
  2. temperatureat reflux for 10 hours
  3. customAfter this time the solvent was removed in vacuo
  4. customthe residue partitioned between diethyl ether and water
  5. customThe organic phase was separated
  6. washwashed with water and brine
  7. dry with materialbefore drying over anhydrous magnesium sulphate
  8. customThe solvent was removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-c4231ee7bb5640f5a60a84c9ecb89209
Quelldatensatz
uspto-grants-1992_05
Patentnummer
US05116862

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