Ethyl Acetoacetate → Ethyl 2Z-[(4-hexylphenyl)methylene]-3-oxobutanoate

HRID 1198213

Reaktionsgleichung

Reaktionsgleichung von HRID 1198213
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].[CH2:10]([C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>N1CCCCC1>[CH2:10]([C:16]1[CH:23]=[CH:22][C:19](/[CH:20]=[C:2](/[C:3](=[O:4])[CH3:5])\[C:1]([O:7][CH2:8][CH3:9])=[O:6])=[CH:18][CH:17]=1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Komponenten

4

Edukt 2

HCID 8868Ethyl AcetoacetateHCID 170813Benzaldehyde, 4-hexyl-

Produkt 1

HCID 67820812Ethyl 2Z-[(4-hexylphenyl)methylene]-3-oxobutanoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8082PiperidineKatalysator

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

Ethyl acetoacetate (3.9g, 0.03 moles), parahexylbenzaldehyde (3.8g, 0.02 moles) and piperidine (3 drops) were stirred at room temperature for 20 hrs. and then stirred for 4 days at 70° C. Products A and B were separated and purified by silica gel chromatography. Structure assignments were supported by NMR, infrared and uv spectra and elemental analysis (302.4).

Aufarbeitung

  1. customProducts A and B were separated
  2. custompurified by silica gel chromatography

Quellen und Nachweise

ORD-Eintrag
ord-aa282224ed5b4f9c861e2e466cf56d88
Quelldatensatz
uspto-grants-1994_01
Patentnummer
US05280047

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