Beta-Alanine → N-Acetyl-beta-alanine

HRID 12008

Reaktionsgleichung

Reaktionsgleichung von HRID 12008
[NH2:1][CH2:2][CH2:3][C:4]([OH:6])=[O:5].C(#N)C.[C:10](OC(=O)C)(=[O:12])[CH3:11]>C([O-])(O)=O.[Na+]>[C:10]([NH:1][CH2:2][CH2:3][C:4]([OH:6])=[O:5])(=[O:12])[CH3:11]

Komponenten

5

Edukt 3

HCID 239Beta-AlanineHCID 6342AcetonitrileHCID 7918Acetic Anhydride2×

Produkt 1

HCID 76406N-Acetyl-beta-alanine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 516892Sodium BicarbonateLösungsmittel

Versuchsvorschrift

To a solution of β-alanine (2.25 g, 25 mmol) in aq. NaHCO3 (15 mL) was added acetonitrile (15 mL) and acetic anhydride (2.55 g, 25 mmol). The reaction mixture was stirred at room temperature for 3 h. Acetic anhydride (2.55 g, 25 mmol) was added and after 2 h and pH was adjusted to 4-5 by addition of NaH2PO4.

Quellen und Nachweise

ORD-Eintrag
ord-8e758045aae44395ac6c2925d1fafcd3
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07727713B2

Verknüpfte Notizen

Wird geladen…