Alpha-Aminobutyric Acid → 2-(Acetylamino)butanoic acid

HRID 1241487

Reaktionsgleichung

Reaktionsgleichung von HRID 1241487
[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>C(O)(=O)C>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

Komponenten

4

Edukt 2

HCID 6657Alpha-Aminobutyric AcidHCID 7918Acetic Anhydride

Produkt 1

HCID 3061072-(Acetylamino)butanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

163 g (1.58 mol) 2-aminobutanoic acid are dissolved in acetic acid, and 242 g (2.37 mol) acetic anhydride are added dropwise. The mixture is stirred for 2 h at 100° C. until completion of reaction, then the solution evaporated to dryness in vacuo. The solid residue is suspended in ethyl acetate, filtered and washed with diethyl ether.

Aufarbeitung

  1. customthe solution evaporated to dryness in vacuo
  2. filtrationfiltered
  3. washwashed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-1f439a35aca34f5790b48824d706b12d
Quelldatensatz
uspto-grants-2006_10
Patentnummer
US07115602B2

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