Hydrochloric Acid → HCID 20279438, Verbindung

HRID 1248354Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1248354
Cl.CC[O:4]CCO.[Cl:8][C:9]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:10]=1[C:11]([C:13]1[C:22]([OH:23])=[CH:21][C:16]2[C:17]([C:19]#[N:20])=[CH:18][C:15]=2[CH:14]=1)=[O:12]>O>[Cl:8][C:9]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:10]=1[C:11]([C:13]1[C:22]([OH:23])=[CH:21][C:16]2[C:17]([C:19]([NH2:20])=[O:4])=[CH:18][C:15]=2[CH:14]=1)=[O:12]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 8076Glycol monoethyl etherHCID 20279442HCID 20279442, Verbindung

Produkt 1

HCID 20279438HCID 20279438, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

20 ml of concentrated hydrochloric acid and 10 ml of Cellosolve are added to 2 g of 4-(2,6-dichlorobenzoyl)-5-hydroxybenzocyclobutene-1-carbonitrile and stirring is carried out for 2 days at room temperature. 100 ml of water are added with stirring and the whole is filtered with suction and recrystallised from ether/hexane. 4-(2,6-dichlorobenzoyl)-5-hydroxybenzocyclobutene-1-carboxamide is obtained having a melting point of 174°.

Aufarbeitung

  1. stirringwith stirring
  2. filtrationthe whole is filtered with suction
  3. customrecrystallised from ether/hexane

Quellen und Nachweise

ORD-Eintrag
ord-3edb071e37af45968eb1a7f09e5cade2
Quelldatensatz
uspto-grants-1985_06
Patentnummer
US04523030

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