Dimethylformamide → 3-bromo-5-(2,6-difluorophenyl)-2-{[2-(trimethylsilyl)ethoxy]methyl}-7-(1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrazol-4-yl)-2H-pyrazolo[4,3-c]isoquinoline

Reaktionsgleichung

[Br:1][C:2]1[N:3]([CH2:28][O:29][CH2:30][CH2:31][Si:32]([CH3:35])([CH3:34])[CH3:33])[N:4]=[C:5]2[C:14]3[CH:13]=[CH:12][C:11]([C:15]4[CH:16]=[N:17][NH:18][CH:19]=4)=[CH:10][C:9]=3[C:8]([C:20]3[C:25]([F:26])=[CH:24][CH:23]=[CH:22][C:21]=3[F:27])=[N:7][C:6]=12.CN(C=O)C.C(N(C(C)C)CC)(C)C.[CH3:50][Si:51]([CH3:58])([CH3:57])[CH2:52][CH2:53][O:54][CH2:55]Cl>O>[Br:1][C:2]1[N:3]([CH2:28][O:29][CH2:30][CH2:31][Si:32]([CH3:35])([CH3:34])[CH3:33])[N:4]=[C:5]2[C:14]3[CH:13]=[CH:12][C:11]([C:15]4[CH:16]=[N:17][N:18]([CH2:55][O:54][CH2:53][CH2:52][Si:51]([CH3:58])([CH3:57])[CH3:50])[CH:19]=4)=[CH:10][C:9]=3[C:8]([C:20]3[C:21]([F:27])=[CH:22][CH:23]=[CH:24][C:25]=3[F:26])=[N:7][C:6]=12