Pyridine → HCID 12922684, Verbindung

HRID 1277916

Reaktionsgleichung

Reaktionsgleichung von HRID 1277916
[P:1](=[O:7])([NH2:6])([S:4][CH3:5])[O:2][CH3:3].N1C=CC=CC=1.Cl[S:15][N:16]([CH:23]([CH3:25])[CH3:24])[C:17](=[O:22])[O:18][CH2:19][CH2:20][CH3:21].Cl.N1C=CC=CC=1.S(Cl)Cl>C(Cl)Cl>[CH2:19]([O:18][C:17]([N:16]([CH:23]([CH3:24])[CH3:25])[S:15][NH:6][P:1](=[O:7])([S:4][CH3:5])[O:2][CH3:3])=[O:22])[CH2:20][CH3:21]

Komponenten

7

Edukt 5

HCID 1049PyridineHCID 4096MethamidophosHCID 25353Sulfur dichloride2×HCID 10176127Pyridinium chlorideHCID 12922683HCID 12922683, Verbindung

Produkt 1

HCID 12922684HCID 12922684, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a stirred mixture of 4.0 g (0.028 mol) O,S-dimethyl phosphoramidothioate, 2.2 g pyridine (0.028 mol) and 15 ml of anhydrous methylene chloride, chilled to 0°-5° C., was added dropwise 6.0 g (0.028 mol) propyl (chlorosulfenyl)(isopropyl)carbamate over a period of 15 minutes. Pyridine hydrochloride forms immediately during addition of the sulfenyl chloride. The reaction mixture was stirred for an additional half hour at room temperature after the addition of the sulfenyl chloride.

Aufarbeitung

  1. temperaturechilled to 0°-5° C.

Quellen und Nachweise

ORD-Eintrag
ord-c35fd00e208c42c198d6462c8173f4f0
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04279897

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