Glycol monoethyl ether → HCID 21163083, Verbindung

HRID 1278236Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1278236
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1.[CH2:21]([O:23]CCO)[CH3:22].[H-].[Na+].[H-]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]([O:18][CH2:19][CH2:20][O:23][CH2:21][CH3:22])=[O:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1

Komponenten

5

Edukt 4

HCID 8076Glycol monoethyl etherHCID 24758Sodium hydrideHCID 166653HydrideHCID 11196438ETHYL 7-(PYRIDIN-3-YL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLATE

Produkt 1

HCID 21163083HCID 21163083, Verbindung

Versuchsvorschrift

To a mixture of ethyl 7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate and 2-ethoxyethanol is added sodium hydride. After the hydride is reacted, the mixture is heated on a steam bath for 12 hours. The solvent is removed and the residue is acidified with dilute acetic acid to give the product of the example.

Aufarbeitung

  1. temperaturethe mixture is heated on a steam bath for 12 hours
  2. customThe solvent is removed
  3. customto give the product of the example

Quellen und Nachweise

ORD-Eintrag
ord-990130447918491cb3a08531fd5ef381
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04281000

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